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Shaanxi International Medical Exchange Promotion Association Vice President, Professor Mou Jianjun's Team from the First Affiliated Hospital of Xi'an Jiaotong University Publishes Latest Findings in Diabetes Care: Highlighting the Importance of Lifelong Weight Management

Professor Mu Jianjun's team from the First Affiliated Hospital of Xi' an Jiaotong University, vice president of Shaanxi International Medical Exchange Promotion Association, published the latest results in Diabetes Care: revealing the importance of life-cycle weight management

Recently, the research team led by Professor Mou, Jianjun from the First Affiliated Hospital of Xi'an Jiaotong University published their latest study in the internationally renowned journal Diabetes Care (Impact Factor: 16.6), titled “Transition of BMI Status From Childhood to Adulthood and Cardiovascular-Kidney-Metabolic Syndrome in Midlife: A 36-Year Cohort Study.” Associate Researcher Wang, Yang from the First Affiliated Hospital of Xi'an Jiaotong University, along with graduate students Yang, Yang and Chen, Jing from the School of Public Health at Peking University, are co-first authors. Professor Mou, Jianjun (Vice President of the Shaanxi International Medical Exchange Promotion Association) and Associate Professor Liu, Zheng from the School of Public Health at Peking University are the corresponding authors.

Cardiovascular-Kidney-Metabolic (CKM) syndrome is a multisystem metabolic disorder resulting from the interaction of obesity, diabetes, chronic kidney disease, and cardiovascular disease, significantly increasing the risk of cardiovascular events and all-cause mortality. The global burden of CKM-related diseases continues to rise, with obesity serving as a key driving factor throughout the life course.

Based on the “Hanzhong Childhood Hypertension Cohort,” this study is the first to systematically reveal that dynamic changes in BMI from childhood to midlife are closely associated with the risk of CKM syndrome in midlife. The findings provide critical evidence supporting early-life interventions in obesity prevention and control strategies.

The authors extend their gratitude to Professor Gregory Y. H. Lip from the University of Liverpool and Professor Duo-Lao Wang from the Liverpool School of Tropical Medicine for their strong support. This research was funded by the National Natural Science Foundation of China, the Shaanxi Provincial Key Research and Development Program, and the Clinical Research Center Key Project of the First Affiliated Hospital of Xi'an Jiaotong University.